Ingredients Wiki

Clinical Findings

• A landmark study published in Reproductive Biology and Endocrinology showed a 42% average increase in free testosterone after 12 days of daily 3.12g DAA supplementation.
• Research in Journal of the International Society of Sports Nutrition suggests standard clinical 2-3g doses are optimal; resistance-trained men should avoid excess doses (6g+) to prevent feedback regulation.

Safety & Tolerability

Excellent safety profile at clinical doses. Minor side effects might include mild digestive discomfort if taken on an empty stomach. No hepatic or renal strain reported in literature.

Clinical Findings

• A double-blind, randomized, placebo-controlled study published in the Indian Journal of Psychological Medicine demonstrated a 27.9% reduction in serum cortisol levels alongside significant improvements in stress assessment scales.
• Research in the Journal of the International Society of Sports Nutrition showed that participants taking KSM-66® experienced a 16.7% increase in serum testosterone levels and significantly greater increases in muscle strength and recovery.

Safety & Tolerability

Excellent safety profile with no significant adverse events reported in clinical trials. As an adaptogen, it naturally supports somatic equilibrium. Individuals with nightshade sensitivities should use caution.

Clinical Findings

• A classic study published in the journal Nutrition showed that restricting dietary zinc in healthy young men led to a 50% drop in serum testosterone after 20 weeks, while zinc supplementation in marginally zinc-deficient elderly men doubled testosterone levels.
• Research on elite athletes demonstrated that zinc supplementation prevents the exercise-induced depletion of thyroid hormones and testosterone, preserving athletic performance capacity.

Safety & Tolerability

Extremely safe at standard dietary doses. Prolonged daily dosages exceeding 40-50mg should be balanced with small amounts of copper to prevent secondary copper deficiencies.

Clinical Findings

• A randomized controlled trial published in Hormone and Metabolic Research found that men receiving 3,332 IU of Vitamin D3 daily for a year experienced a significant increase in total testosterone (from 10.7 to 13.4 nmol/L) and free testosterone.
• Cohort studies demonstrate a direct linear correlation between serum 25-hydroxyvitamin D levels and circulating bioactive testosterone levels in healthy males.

Safety & Tolerability

Extremely safe up to 10,000 IU daily. Periodic blood testing is recommended for long-term high-dose supplementation to verify optimal blood range (50-80 ng/mL) and avoid hypercalcemia.

Clinical Findings

• A clinical trial published in Phytotherapy Research showed that 600mg of Fenugreek extract daily for 6 weeks significantly improved sexual arousal, muscle strength, and self-reported energy levels in healthy men.
• A double-blind study observed a significant increase in both free and total testosterone levels, along with reductions in body fat percentage, over an 8-week resistance training program.

Safety & Tolerability

Very well tolerated. A common, harmless side effect is a faint maple syrup odor in sweat or urine. Individuals with severe allergies to chickpeas or peanuts should exercise caution.

Clinical Findings

• Transporter research shows AstraGin® significantly upregulates absorption transporters like CAT1 (amino acids) and SGLT1 (glucose) by up to 50% to 200% in intestinal epithelial cells.
• Intestinal health trials demonstrate that AstraGin® helps restore damaged microvilli and reduces gut wall inflammation, improving the physical absorption area for complex compounds.

Safety & Tolerability

GRAS (Generally Recognized as Safe) affirmed. Composed of natural astragalus and ginseng extracts, it has zero reported toxicities or adverse interactions at clinical dosage thresholds.

Clinical Findings

• A systematic review in the British Journal of Clinical Pharmacology concluded that red ginseng is effective in clinical trials for improving erectile function and sexual performance compared to placebo.
• Studies on physical performance indicate that ginsenosides reduce muscle damage markers (like creatine kinase) and systemic oxidative stress after intense exercise.

Safety & Tolerability

Highly safe for long-term consumption. Since it possesses mild adaptogenic stimulant properties, individuals taking blood pressure or diabetic medications should consult a physician.

Clinical Findings

• Research published in Journal of Herbal Pharmacotherapy indicates that stinging nettle lignans bind strongly to SHBG, inhibiting the binding of active testosterone to transport globulins, thereby raising free testosterone.
• Clinical observations confirm that nettle leaf compounds possess mild 5-alpha-reductase inhibitory action, helping to regulate the conversion of testosterone into DHT, supporting prostate health.

Safety & Tolerability

Excellent safety history. It has a mild diuretic effect; ensure adequate daily hydration. Minor stomach upset occurs in less than 1% of clinical trial participants.

Clinical Findings

• A study in the Journal of Trace Elements in Medicine and Biology showed that daily supplementation of 10mg of Boron for just one week significantly increased free testosterone levels and decreased SHBG and estrogen.
• Research on athletes taking Magnesium showed that supplementation increases both free and total testosterone levels, with greater benefits observed in active subjects.

Safety & Tolerability

Extremely high safety index. Excess magnesium can cause mild laxative effects if taken in isolation at extreme dosages. The formulated clinical amounts are safe and well-tolerated.